TB-500
Actin regulation and angiogenesis for recovery
Overview
TB-500 is a synthetic version of the naturally occurring peptide Thymosin Beta-4 (Tβ4). It plays a crucial role in tissue repair by regulating actin, a key protein in cell structure and movement, and promoting new blood vessel formation.
Mechanism of Action
Sequesters G-actin → promotes cell migration and differentiation → upregulates angiogenesis → reduces inflammation → promotes hair follicle stem cell migration → crosses blood-brain barrier.
Benefits
- Enhanced tissue repair
- Reduced inflammation
- New blood vessel formation
- Improved flexibility
- Hair regrowth potential
- Cardiac repair
Dosing Protocol
Half-Life
~4–6 hours (but effects last days)
Duration of pharmacological activity after administration.
Side Effects
- Headache
- Lethargy (temporary)
- Head rush post-injection
- Generally well-tolerated
Stacking Recommendations
Storage & Reconstitution
Lyophilized: -20°C. Reconstituted: 2–8°C, use within 21 days.
Research Notes
Extensively studied for wound healing and cardiac repair. Phase 1/2 trials for cardiac applications. Tβ4 is present in all cells and plays fundamental roles in tissue development and repair.
Medical Disclaimer
This information is provided for educational and research purposes only. It is not intended as medical advice, diagnosis, or treatment recommendations. Peptide therapy should only be initiated under the supervision of a qualified healthcare provider. Individual results may vary. Always consult with your physician before starting any new therapy. Regulatory status varies by jurisdiction.