Agefocus

Blends & Mixtures

Curated peptide stacks with synergistic combinations for specific therapeutic goals.

Weight Loss Stacks

Semaglutide + BPC-157

Weight loss with gut protection

This stack combines the powerful appetite-suppressing and metabolic effects of semaglutide with the gut-healing and tissue-protective properties of BPC-157. The addition of BPC-157 helps mitigate the common GI side effects of semaglutide while providing synergistic metabolic benefits.

Components

SemaglutideGLP-1 agonist for appetite suppression and weight loss
BPC-157Gut protection, reduces nausea, tissue healing

Benefits

Enhanced weight loss with reduced GI side effects Gut lining protection Improved tolerance to GLP-1 therapy Tissue repair support
Semaglutide: 0.25–2.4 mg/week (SubQ) | BPC-157: 250–500 mcg/day (SubQ or oral)
Subcutaneous Injection

Start semaglutide at low dose and titrate up. BPC-157 can be started concurrently to preemptively protect the GI tract. Many practitioners report significantly reduced nausea with this combination.

Weight Loss Stacks

Tirzepatide + BPC-157

Weight loss with tissue protection

Combines the dual GLP-1/GIP agonism of tirzepatide with BPC-157's tissue repair capabilities. This stack maximizes weight loss potential while protecting the gastrointestinal system and supporting overall tissue health during rapid weight loss.

Components

TirzepatideDual GLP-1/GIP agonist for maximum weight loss
BPC-157Tissue protection and GI support

Benefits

Superior weight loss (up to 22.5%) GI protection during aggressive treatment Tissue integrity during rapid weight loss Reduced side effects
Tirzepatide: 2.5–15 mg/week (SubQ) | BPC-157: 250–500 mcg/day (SubQ or oral)
Subcutaneous Injection

Tirzepatide's dual mechanism provides superior weight loss. BPC-157 addresses GI complaints and supports skin elasticity during significant weight changes. Monitor closely during dose escalation.

Weight Loss Stacks

Formula WL-6250

Metabolic health support formula

A comprehensive metabolic support formula designed for overall metabolic optimization. This blend combines multiple pathways targeting fat metabolism, insulin sensitivity, and cellular energy production for sustained weight management.

Components

AOD-9604HGH fat-loss fragment for targeted lipolysis
MOTS-cMitochondrial peptide for metabolic enhancement
5-Amino-1MQNNMT inhibitor for NAD+ boost

Benefits

Multi-pathway fat loss Metabolic rate enhancement Mitochondrial optimization No GLP-1 side effects
AOD-9604: 300 mcg/day | MOTS-c: 5 mg 3x/week | 5-Amino-1MQ: 100 mg/day oral
Subcutaneous Injection + Oral

This non-GLP-1 approach targets fat metabolism through three distinct mechanisms. Ideal for patients who cannot tolerate GLP-1 agonists or prefer a non-hormonal approach to weight management.

Weight Loss Stacks

KLOW Capsules

Oral capsules for metabolic health

An oral metabolic support formulation designed for patients who prefer non-injectable options. Contains peptides and compounds with oral bioavailability targeting appetite regulation, fat metabolism, and energy production.

Components

5-Amino-1MQOral NAD+ booster and NNMT inhibitor
KPVAnti-inflammatory gut support
MK-677Oral GH secretagogue

Benefits

Completely oral—no injections required Metabolic support Gut health improvement GH optimization
As directed per capsule formulation. Typically once or twice daily with food.
Oral

Ideal for patients who are needle-averse. Provides metabolic support through multiple oral-bioavailable compounds. Monitor blood glucose with MK-677 inclusion.

Metabolic Optimization Series

Formula M-51

Metabolic series peptide blend

A targeted metabolic optimization formula designed to enhance fat oxidation and energy metabolism through complementary pathways. This blend focuses on improving metabolic flexibility and mitochondrial efficiency.

Components

MOTS-cExercise mimetic and AMPK activator
5-Amino-1MQNAD+ optimization
AOD-9604Targeted fat metabolism

Benefits

Enhanced metabolic flexibility Improved fat oxidation Mitochondrial optimization NAD+ restoration
MOTS-c: 5 mg 3x/week | 5-Amino-1MQ: 100 mg/day | AOD-9604: 300 mcg/day
Subcutaneous Injection + Oral

Designed for active individuals seeking metabolic optimization. Best combined with regular exercise for maximal mitochondrial benefits.

Metabolic Optimization Series

Formula M-2531

Advanced metabolic optimization

An advanced metabolic optimization protocol combining multiple pathways for comprehensive metabolic enhancement. This formula targets both central and peripheral metabolic processes for maximum effect.

Components

TesofensineCentral appetite suppression
5-Amino-1MQNNMT inhibition and NAD+ boost
MOTS-cMitochondrial metabolic signaling
Fragment 176-191Direct lipolysis

Benefits

Central and peripheral metabolic enhancement Multi-pathway fat loss Appetite control Energy optimization
Tesofensine: 0.25 mg/day | 5-Amino-1MQ: 100 mg/day | MOTS-c: 5 mg 3x/week | Frag 176-191: 250 mcg 2x/day
Oral + Subcutaneous Injection

Advanced protocol for experienced practitioners. Monitor cardiovascular parameters with tesofensine. Not first-line—reserve for patients with inadequate response to simpler protocols.

Metabolic Optimization Series

Formula M-Shred

Triple-compound: BAM-15 + SLU-PP-332 + C15

A cutting-edge metabolic shredding formula combining three exercise mimetic compounds. This stack targets mitochondrial uncoupling, ERRα activation, and cellular energy metabolism for maximum fat oxidation.

Components

BAM-15Mitochondrial uncoupler for energy expenditure
SLU-PP-332ERRα agonist—exercise mimetic
C15 (Pentadecanoic acid)Odd-chain fatty acid for mitochondrial support

Benefits

Maximum fat oxidation Exercise mimetic effects Mitochondrial optimization Energy expenditure increase
Per research protocol guidelines. Doses vary by compound. Consult literature.
Oral

Experimental stack using novel exercise mimetic compounds. Limited human data for BAM-15 and SLU-PP-332. C15 is commercially available. For research and clinical exploration only.

Growth Hormone Stacks

CJC-1295 + Ipamorelin

Classic GH optimization stack

The gold standard GH peptide stack combining GHRH (CJC-1295) with GHRP (Ipamorelin). This synergistic combination produces a significantly greater GH pulse than either peptide alone while maintaining an excellent safety profile.

Components

CJC-1295GHRH analog—primes pituitary for GH release
IpamorelinSelective GH secretagogue—triggers GH pulse

Benefits

Synergistic GH release (3–5x greater than individual) Clean GH pulse without cortisol spike Anti-aging benefits Improved sleep quality
CJC-1295: 100–300 mcg + Ipamorelin: 100–300 mcg | Combined in single injection
Subcutaneous Injection

Most prescribed GH peptide stack worldwide. Inject 30 minutes before bed on empty stomach for optimal GH release during sleep. Can also be dosed in the morning. Avoid carbs 30 min before/after.

Growth Hormone Stacks

GHRP-2 + CJC-1295

GH stimulation combo

A more aggressive GH optimization stack pairing the potent GHRP-2 with CJC-1295. This combination produces higher GH peaks than the ipamorelin version but with more pronounced side effects including appetite stimulation.

Components

GHRP-2Potent GH secretagogue via ghrelin pathway
CJC-1295GHRH analog for sustained GH elevation

Benefits

Maximum GH release Strong IGF-1 elevation Enhanced appetite (beneficial for bulking) Improved recovery
GHRP-2: 100–300 mcg + CJC-1295: 100–300 mcg | 2–3x daily
Subcutaneous Injection

More potent than CJC/Ipamorelin stack but with more appetite stimulation and cortisol elevation. Better suited for individuals seeking maximum GH output or those who benefit from appetite increase.

Growth Hormone Stacks

Ipamorelin + Sermorelin

Synergistic GH release

A gentle yet effective GH optimization stack combining two well-characterized peptides. Sermorelin provides the GHRH signal while ipamorelin adds the GHRP stimulus, creating a physiologic GH pulse with minimal side effects.

Components

IpamorelinSelective GH secretagogue with clean profile
SermorelinFDA-approved GHRH analog

Benefits

Well-characterized safety profile Natural GH pulsatility Gentle introduction to GH therapy Anti-aging benefits
Ipamorelin: 100–200 mcg + Sermorelin: 200–300 mcg | Once daily at bedtime
Subcutaneous Injection

Ideal first GH peptide stack for beginners. Both peptides have extensive safety data. Sermorelin's FDA history adds confidence. Inject before bed for optimal sleep-related GH release.

Recovery & Healing Stacks

BPC-157 + TB-500

Ultimate recovery blend

The most popular healing peptide stack, combining BPC-157's tissue repair with TB-500's anti-inflammatory and angiogenic properties. Together they address healing from multiple angles for accelerated recovery from injuries.

Components

BPC-157Tissue repair, gut healing, and cytoprotection
TB-500Actin regulation, angiogenesis, and anti-inflammation

Benefits

Synergistic tissue repair Faster injury recovery Reduced inflammation New blood vessel formation
BPC-157: 250–500 mcg/day (SubQ near injury) | TB-500: 2–5 mg 2x/week (loading), 1–2 mg/week (maintenance)
Subcutaneous Injection

The “Wolverine stack.” BPC-157 provides local tissue repair while TB-500 offers systemic anti-inflammatory and regenerative effects. Can inject BPC-157 near injury site for targeted healing.

Recovery & Healing Stacks

BPC-157 + GHK-Cu

Tissue repair and skin

A stack combining internal tissue repair (BPC-157) with skin and connective tissue regeneration (GHK-Cu). Ideal for post-surgical recovery, wound healing, and aesthetic applications.

Components

BPC-157Internal tissue repair and gut healing
GHK-CuSkin rejuvenation, collagen synthesis, gene regulation

Benefits

Comprehensive tissue repair Skin rejuvenation Collagen synthesis Wound healing acceleration
BPC-157: 250–500 mcg/day (SubQ) | GHK-Cu: 1–3 mg/day (SubQ or topical)
Subcutaneous Injection + Topical

Excellent post-surgical recovery stack. GHK-Cu can be applied topically to surgical sites while BPC-157 works systemically. Also popular for anti-aging skin protocols.

Recovery & Healing Stacks

Thymosin Alpha-1 + BPC-157

Immune + healing

Combines immune system optimization with tissue repair for comprehensive recovery support. This stack is particularly useful during illness recovery, post-infection healing, and for immunocompromised patients.

Components

Thymosin Alpha-1Immune system modulation and enhancement
BPC-157Tissue repair and anti-inflammatory support

Benefits

Immune system optimization Tissue repair during illness Anti-inflammatory synergy Gut immune support
Thymosin Alpha-1: 1.6 mg 2x/week (SubQ) | BPC-157: 250–500 mcg/day (SubQ)
Subcutaneous Injection

Valuable for patients recovering from chronic infections or illness. TA1 boosts immune surveillance while BPC-157 repairs any tissue damage. Also used prophylactically during flu season or travel.