Kisspeptin-10
Hormonal regulator for reproductive health
Overview
Kisspeptin-10 is a truncated form of kisspeptin, the master regulator of the reproductive hormone cascade. It directly stimulates GnRH neurons, making it a key modulator of the hypothalamic-pituitary-gonadal (HPG) axis.
Mechanism of Action
Activates KISS1R (GPR54) on GnRH neurons → stimulates GnRH pulsatile release → increases LH and FSH secretion → enhances testosterone and estrogen production → potential fertility restoration.
Benefits
- HPG axis stimulation
- Natural testosterone boost
- Fertility support
- LH/FSH normalization
- Reproductive health optimization
Dosing Protocol
Half-Life
~28 minutes
Duration of pharmacological activity after administration.
Side Effects
- Headache
- Nausea
- Abdominal discomfort
- Hot flashes
- Generally well-tolerated
Stacking Recommendations
Storage & Reconstitution
Lyophilized: -20°C. Reconstituted: 2–8°C, use within 7 days.
Research Notes
Active research in IVF protocols as alternative to hCG for ovulation trigger. Studies show restoration of HPG axis in hypothalamic amenorrhea. Potential for male hypogonadism treatment.
Medical Disclaimer
This information is provided for educational and research purposes only. It is not intended as medical advice, diagnosis, or treatment recommendations. Peptide therapy should only be initiated under the supervision of a qualified healthcare provider. Individual results may vary. Always consult with your physician before starting any new therapy. Regulatory status varies by jurisdiction.