Hexarelin
GH secretagogue with cardiac benefits
Overview
Hexarelin is a synthetic hexapeptide GH secretagogue known for producing the strongest acute GH release among GHRPs. It also has notable cardioprotective properties independent of its GH-releasing effects.
Mechanism of Action
Activates GHS-R1a receptors → maximum GH pulse release → cardiac protective via CD36 receptor binding → anti-fibrotic cardiac effects independent of GH pathway.
Benefits
- Strongest GH release among GHRPs
- Cardioprotective properties
- Improved cardiac function
- Enhanced recovery
- Neuroprotective effects
Dosing Protocol
Half-Life
~70 minutes
Duration of pharmacological activity after administration.
Side Effects
- Elevated cortisol
- Prolactin increase
- Water retention
- Desensitization over time
- Appetite increase
Stacking Recommendations
Storage & Reconstitution
Lyophilized: -20°C. Reconstituted: 2–8°C, use within 21 days.
Research Notes
Unique among GHRPs for documented cardioprotective effects. Desensitization limits long-term use. Studies show protection against cardiac ischemia and fibrosis.
Medical Disclaimer
This information is provided for educational and research purposes only. It is not intended as medical advice, diagnosis, or treatment recommendations. Peptide therapy should only be initiated under the supervision of a qualified healthcare provider. Individual results may vary. Always consult with your physician before starting any new therapy. Regulatory status varies by jurisdiction.