GHK-Cu
Copper peptide for genome regulation and skin
Overview
GHK-Cu is a naturally occurring copper-binding tripeptide found in human plasma, saliva, and urine. It has remarkable gene-regulatory properties, affecting over 4,000 genes, and is known for its skin rejuvenation, wound healing, and anti-aging effects.
Mechanism of Action
Binds copper → modulates 4,000+ gene expressions → promotes collagen synthesis → activates tissue remodeling → anti-oxidant via SOD activation → stimulates glycosaminoglycan synthesis → attracts immune cells for repair.
Benefits
- Skin rejuvenation and tightening
- Wound healing acceleration
- Hair growth stimulation
- Anti-inflammatory
- Collagen and elastin synthesis
- Gene expression regulation
Dosing Protocol
Half-Life
~1 hour (but gene effects persist)
Duration of pharmacological activity after administration.
Side Effects
- Injection site irritation
- Skin sensitivity (topical)
- Generally very safe
Stacking Recommendations
Storage & Reconstitution
Lyophilized: -20°C. Reconstituted: 2–8°C, use within 14 days. Topical: per manufacturer.
Research Notes
One of the most studied peptides for skin and tissue repair. Natural decline with age (200 ng/mL at 20 → 80 ng/mL at 60). Over 140 genes reset to healthy patterns. Widely used in dermatology.
Medical Disclaimer
This information is provided for educational and research purposes only. It is not intended as medical advice, diagnosis, or treatment recommendations. Peptide therapy should only be initiated under the supervision of a qualified healthcare provider. Individual results may vary. Always consult with your physician before starting any new therapy. Regulatory status varies by jurisdiction.