5-Amino-1MQ
NAD+ booster for metabolic optimization and fat loss
Overview
5-Amino-1MQ is a small molecule that blocks the enzyme NNMT (nicotinamide N-methyltransferase), which plays a key role in energy metabolism and fat cell regulation. By inhibiting NNMT, it increases NAD+ levels and activates SIRT1, promoting fat loss and metabolic health.
Mechanism of Action
Inhibits NNMT enzyme → increases intracellular NAD+ → activates SIRT1 pathway → enhances fat oxidation and reduces adipogenesis.
Benefits
- Increases NAD+ levels
- Promotes fat cell shrinkage
- Enhances metabolic rate
- Supports lean muscle mass
- Oral bioavailability
Dosing Protocol
Half-Life
~12 hours
Duration of pharmacological activity after administration.
Side Effects
- Mild GI discomfort
- Headache (rare)
- Generally well-tolerated
Stacking Recommendations
Storage & Reconstitution
Store at room temperature in a cool, dry place. Protect from moisture and light.
Research Notes
Preclinical studies show significant reduction in body fat and improved metabolic markers in animal models. Human clinical trials are ongoing. NNMT inhibition is an emerging target in obesity research.
Medical Disclaimer
This information is provided for educational and research purposes only. It is not intended as medical advice, diagnosis, or treatment recommendations. Peptide therapy should only be initiated under the supervision of a qualified healthcare provider. Individual results may vary. Always consult with your physician before starting any new therapy. Regulatory status varies by jurisdiction.